莫西沙星与左氧氟沙星治疗下呼吸道感染的临床对比

Comparative Analysis of Clinical Efficacy of Moxifloxacin and Levofloxacin in Treatment of Lower Respiratory Tract Infection

目的比较莫西沙星与左氧氟沙星治疗下呼吸道感染的临床疗效。方法选取2017年1月至12月本院收治的76例下呼吸道感染患者,按照治疗方式不同分为左氧氟沙星组(38例)和莫西沙星(38例),分别予以左氧氟沙星和莫西沙星治疗,比较两组患者临床疗效、不良反应和治疗成本效果。结果莫西沙星组临床治疗总有效率为94.7%,显著高于左氧氟沙星组(78.9%,P<0.05);莫西沙星组患者发热消失时间、喘息消失时间和咳嗽消失时间均明显少于左氧氟沙星组(P<0.05);莫西沙星组患者成本效果明显低于左氧氟沙星组;两组患者均未见严重不良反应发生。结论左氧氟沙星与莫西沙星均能有效治疗下呼吸道感染疾病,莫西沙星能快速改善患者临床症状,左氧氟沙星组患者成本效果好于莫西沙星组。

Objective To compare the clinical efficacy and cost of mosifloxacin and levofloxacin in the treatment of lower respiratory tract infections. Methods Seventy-six patients with lower respiratory tract infection in our hospital from January to December 2017 were divided into levofloxacin group(38 cases)and mosifloxacin group(38 cases)according to different treatment Methods. The clinical efficacy,side effects and treatment cost of the two groups were compared. Results The total effective rate of the mosifloxacin group was 94.7%,significantly higher than that of levofloxacin group(78.9%,P<0.05). The disappearance time of fever,gasp and cough in the moxifloxacin group were significantly less than those in the levofloxacin group(P<0.05). The cost effect of the moxifloxacin group was significantly lower than that of the levofloxacin group. There were no serious adverse reactions in both groups. Conclusion Levofloxacin and moxifloxacin are effective in the treatment of lower respiratory tract infections. Moxifloxacin could rapidly improve the clinical symptoms of patients;while the cost-effectiveness of levofloxacin is better than that of moxifloxacin.