麻醉右美托咪啶对老年骨科患者术后认知能力障碍的影响

Effect of Dexmedetomidine Anesthesia on Postoperative Cognitive Dysfunction in Elderly Patients in Department of Orthopedics

目的观察麻醉右美托咪啶对老年骨科术后认知能力障碍的影响。方法选取2012年本院收治的128例老年骨科患者为研究对象,随机分为观察组和对照组,各64例。对照组采用常规麻醉,观察组在麻醉时采用右美托咪啶。观察两组患者在术后进行术后清醒时间和智能精神状态检查表评分,并对患者的认知能力障碍发病率进行比较。结果观察组患者的术后清醒时间短于对照组(P <0.05),同时患者的智能精神状态检查表评分优于对照组(P <0.05),观察组患者的术后认知能力障碍发病率低于对照组(P <0.05)。结论在老年骨科患者进行手术的过程中,采用右美托咪啶来进行麻醉,具有较好的麻醉效果,可以使患者在术后尽早清醒,有效降低患者术后认知能力障碍发病率。

Objective To explore the effect of dexmedetomidine anesthesia on cognitive impairment after orthopedics. Methods A total of 128 elderly orthopaedic patients admitted to our hospital in 2012 were selected and randomly divided into two groups,with 64 each group. The control group was treated with conventional anesthesia,while the observation group was treated with dexmedetomidine. The post-operative wake-up time and mental state checklist scores of the two groups were observed,and the incidence of cognitive impairment were compare. Results The patients in the observation group had less postoperative waking time than the control group(P<0.05),and the score of the intelligent mental status examination table of the patients was better than the control group(P<0.05),and the incidence of postoperative cognitive impairment of the patients in the observation group was lower than the control group(P<0.05). Conclusion The use of dexmedetomidine for anesthesia in elderly orthopaedic patients has a good anesthetic effect,which can effectively help patients to wake up as soon as possible after surgery and effectively reduce the incidence rate of postoperative cognitive impairment.