肝硬化患者血清生化指标的表达及临床意义

Expression and Clinical Significance of Serum Biochemical indexes in Patients with Liver Cirrhosis

目的探讨肝硬化患者血清生化指标的表达和临床价值。方法选取2016年11月至2018年2月本院收治的肝硬化患者60例作为观察组,选取同期健康体检人员60名作为对照组。两组受试人员均给予血清生化指标检测,观察对比两组受试人员血清网膜素、脂联素与内脏脂肪素指标水平情况。结果观察组患者的血清网膜素、脂联素的水平分别是(924.6±20.6)ng/L、(904.8±21.8)ng/L,显著高于对照组[(728.5±56.4)、(650.8±42.9)ng/L,P <0.05],组间比较差异有统计学意义(P <0.05)。结论肝硬化症状发生时患者的网膜素、脂联素水平会有升高的现象,内脏的脂肪素也会下降,能够作为肝硬化预测指标,但是无法有效评估肝功能的严重程度。

Objective To investigate the expression and clinical value of serum biochemical indexes in patients with liver cirrhosis. Methods Sixty cases of liver cirrhosis in our hospital from November 2016 to February2018 were selected as the observation group,and 60 healthy persons in the same period were selected as the control group. The serum biochemical indexes were detected in the two groups,and the levels of the serum omentin,adiponectin and visceral adiponectin were observed and compared in the two groups. Results The serum levels of omentin and adiponectin in the observation group were 924.6±20.6 and 904.8± 21.8 ng/L,respectively,significantly higher than those in the control group,and there was a significant difference between the two groups(728.5±56.4,650.8±42.9 ng/L,P<0.05). Conclusion The level of retinin and adiponectin in patients with hepatocirrhosis may increase,and the level of adiposin in the viscera may decrease,which can be used as a predictor of cirrhosis,but the severity of liver function may not be evaluated effectively.