上尿路尿路上皮癌术后膀胱复发危险因素分析

Upper Urinary Tract Urothelial Carcinoma Postoperative Bladder Recurrence Risk Factor Analysis

目的浅析上尿路尿路上皮癌(UTUC)患者在接受手术治疗后膀胱复发的危险因素。方法回顾性分析2011年5月至2017年12月在本院接受治疗的190例患者作为受试者,治疗后对其进行定期的随访,分析患者的住院资料,定时进行随访的记录,最后对比统计膀胱复发的数据。结果整理后发现,患者中膀胱复发的共有48例。单个病灶膀胱复发的概率为25.35%,多发病灶患者中复发的概率为47.92%,差异有统计学意义(P <0.05);术前患有慢性肾脏疾病肾病的患者膀胱复发的概率为40.74%,未患该疾病的膀胱复发概率为30.15%,差异有统计学意义(P <0.05)。结论患者的病灶数目、手术前是否患有慢性肾脏疾病,可列入UTUC患者术后膀胱复发的危险因素中。

Objective To analyze the risk factors for recurrence of upper urinary tract epithelial carcinoma(UTUC)after surgery.Methods 190 patients who were treated in our hospital during the 12 months from February2013 to February 2014 were selected as subjects.After treatment,they were followed up regularly to analyze the patient’s hospitalization data,record the follow-up regularly,and finally compare the data of bladder recurrence.Results A total of 48 cases of recurrent bladder were found.The probability of recurrence of a single lesion was 25.35%,and the probability of recurrence in patients with multiple lesions was 47.92%,with differences between the results(P<0.05).The recurrence rate of bladder was 40.74%in patients with chronic kidney disease before operation,and 30.15%in those without the disease,showing a significant difference(P<0.05).Conclusion The number of lesions and whether patients had chronic renal disease before surgery could be included in the risk factors of bladder recurrence after UTUC.