活血补气疗法治疗心脉瘀阻型冠心病的疗效及对炎症因子的影响

Effect of Buqi Huoxue Therapy on Coronary heart Disease with Heart blood Stasis and its Influence on Inflammatory Factors

目的观察活血补气疗法对心脉瘀阻型冠心病的治疗疗效以及对炎症因子的影响。方法选取2016年1月至2018年1月所收治的186例心脉瘀阻型冠心病患者,随机分为对照组(使用硝酸异山梨酯口服片)和治疗组(加用活血补气方),每组各93例。对比两组患者治疗效果、心电图改善情况以及炎症因子水平,包括monocyte chemotactic protein-1(MCP-1)、interleukin-10(IL-10)、tumor necrosis factorα(TNF-α)。结果治疗组治疗效果明显优于对照组,差异具有统计学意义(P <0.05)。治疗组心电图改善明显优于对照组,差异有统计学意义(P <0.05)。治疗组MCP-1、TNF-α水平低于对照组, IL-10水平低于对照组,差异有统计学意义(P <0.05)。结论活血补气疗法对心脉瘀阻型冠心病具有理想的治疗效果,并且对相关炎症反应具有明显的干预作用。

Objective To observe the therapeutic effect of Huoxue Bu Qi therapy on coronary heart disease(CHD)and its effect on inflammatory factors.Methods From January 2016 to January 2018,186 patients with CHD were randomly divided into two groups:The control group(using isosorbide dinitrate orally)and the treatment group(plus Huoxue Fuqi Recipe),93 cases in each group.The treatment effect,the improvement of electrocardiogram and the level of inflammatory factors were compared between the two groups,including monocyte chemical protein-1(MCP-1),Interleukin-10(IL-10),tumor necrosis factor alpha(TNF-α).Results The therapeutic effect of the treatment group was significantly better than that of the control group(P<0.05).The improvement of ECG in the treatment group was significantly better than that in the control group(P<0.05).The levels of MCP-1 and TNF-αin the treatment group were lower than those in the control group,and the levels of IL-10 in the treatment group were lower than those in the control group(P<0.05).Conclusion Huoxue Fuqi Recipe has ideal therapeutic effect on coronary heart disease of blood stasis type,and has obvious intervention effect on related inflammatory reaction.