齐拉西酮联合碳酸锂治疗躁狂症患者的临床效果

Clinical Effect of Ziprasidone Combined with Lithium Carbonate in Treatment of Mania Patients

目的观察齐拉西酮联合碳酸锂治疗躁狂症的临床应用效果。方法入选患者总共82例,均为本院2017年1月至2018年6月收治。采用计算机随机分组方式,将所选取患者平均分成观察组和对照组,各41例。观察组采用齐拉西酮联合碳酸锂方式进行治疗,对照组采用碳酸锂方式进行治疗,对比分析两组患者的临床治疗效果情况。结果观察组患者狂躁评分显著低于对照组,观察组患者治疗后显效率以及总有效率均显著高于对照组(P <0.05)。两组患者药物不良反应发生率比较差异无统计学意义(P> 0.05)。结论齐拉西酮联合碳酸锂治疗躁狂症可显著缓解患者狂躁症状,其临床疗效确切,安全性高。

Objective To analyze the clinical effect of ziprasidone combined with lithium carbonate in the treatment of mania.Methods A total of 82 patients were enrolled,all admitted to our hospital from January2017 to June 2018.The selected patients were divided into the observation group and the control group with41 cases each.The observation group was treated with ziprasidone combined with lithium carbonate,while the control group was treated with lithium carbonate.Results The score of mania in the observation group was significantly lower than that in the control group,and the significant efficiency and total effective rate in the observation group were significantly higher than those in the control group(P<0.05).There was no statistically significant difference in the incidence of adverse drug reactions between the two groups(P>0.05).Conclusion Ziprasidone combined with lithium carbonate in the treatment of mania can significantly alleviate the symptoms of mania patients,its clinical efficacy is accurate,high safety.