特异性转移因子辅助治疗难治性结核的研究(Ⅱ.对难治性肺结核近期临床疗效的初步观察)

The Reserch on the Supplementary Treatment of the Difficult—therapy Pulmonary Tuberculosis by the Special Transfer Factor to M.Tuberculosis (Ⅱ. A perliminary observation of the recent-term therapeutic effect)

本文探讨特异性结核转移因子辅助治疗难治性肺结核的临床近期疗效,就痰菌阴转、病灶吸收、临床症状和副作用等与对照组(20例)进行了比较,结果表明,实验组(27例)痰菌阴转时间快,阴转率高(p<0.05),X线病病灶显吸率高(p<O.05),症状消失快,病人自我感觉极好,在用药过程中,未见任何副作用。转移因子可调节机体体液免疫功能和增强机体细胞免疫功能,从而对促进患者康复和控制结核性传染源均具有极积意义,值得深入研究。

The recent-term therapeutic effect of the supplementary treatment of the difficult-therapy pulmonart tuberculosis by the special Tran sfer Factor to M.tuberculosis was observed in this study. The sputum conversion, the lesionabsorption on X-rate,the clinical symptons and the side-effect in the test group (27 cases) were conpared with the control group(20 cases). The results indicated that the rate of the sputum conversion in test group was higer than that of control group(p<0.05), that the time of sputum conversion in test group was rapider than that of control guoup (see Table 1), that the rate of the significant lesionabsorption on X—rate in the test group was higher than that of control group(p<0.05, Table 2)and that the disappearance of the clinical symptoms in the test group was rapider than that of control group. The any of side-effect caused by the special tuberculour transfor factor had been observed in the treatment. This TF can increase the cell ular immurnologic function and regulate the humarol immunologic funcfion so that it can promate the recovery of the patient with the difficult—therapy pulmonary tuberculosis and control the source of the chronic infection of TB. It can be considered that the special Transfor Factor to M.tuberculosis is one of effect immunoregulatory factor treating the difficult-therapy tuberculosis.