大剂量654-2联合茵陈蒿汤治疗重型乙型病毒性肝炎30例

Application of the bad degree B Viral hepatitis with the great dose of 654-2 associated with Yin Cheng Hao Tang in treating 30 casses

目的研究大剂量654-2联合茵陈蒿汤治疗重型乙型病毒性肝炎的机理与疗效分析。方法随机抽样对照组及治疗组各30例。治疗组在对照组基础上采用大剂量654-2静脉点滴(日达200～320mg)及茵陈蒿汤加味治疗。结果治疗组肝昏迷、肝肾综合症、出血等并发症的发生率低于对照组,对照组病死率50%,而治疗组为23.3%。经统计学处理两组P<0.01,有显著差异。结论大剂量654-2联合茵陈蒿汤可以显著地提高重型乙型病毒性肝炎治愈率、降低病死率,减少并发症发生。

Objective:To investigate the working mechanism and the treatment effect of bad degree B viral hepatitis with a great dose of 654 2 associated with Yin Cheng Hao Tang.Methods: To choose 30 cases by chance from every group either the being studied group or the comparision group the study group was treated with an intravenous infusion of a great dose of 654 2(the used dose was 200～320 mg per day)and Yin Cheng Hao Tang.Results:The complications'incidence,for example, hepatic coma,hepatorenal syndrome HRS,bleeding and so on,in the being studied group was lower than the comparision group.The fatal rate of the comparision group was 60 percent,while the study group was 23 3 percent.These data were worked up by statistic method and the “P”datum gotten was smaller than 0 01.So the difference was distinct.Conclusion:A great dose of 654 2 associated with Yin Cheng Hao Tang can increase distinctly the cured rate of bad degree B viral hepatitis,lower the fatal incidence, and decrease the incidence of complications.