全角膜上皮缺损的临床愈合

Clinical healing after pan-corneal epithelium abrasion

总结12例全角膜范围上皮刮除,观察其愈合情况,认为角膜上皮刮除暴露面为上皮层的基底膜,愈合方式需要通过角膜缘干细胞或残存上皮细胞的增殖和移行来完成。12例中愈合时间最长为7天,最短为2天,平均为3.3±1.65天,男性稍短于女性,年轻人明显短于老年人。9例愈合后表面光滑,无后遗症,2例存在点状上皮剥脱,1例有丝状角膜炎,作者认为在作眼后段手术中尽量避免作大范围的角膜上皮刮除。

12 cases were given complete scraping of corneal epithelium, and their healing processes were observed .After Pan-corneal epithelium abrasion, the healing was due to proliterasions and slides of the stem cells in the limbus or the remained epithelial cells . The healing time ranged from 2-7 days, with the average of 3 .33±1.65 days. the healing time of males was slightly shorter than that of females. While the young markedly shorter than the old . 9 cases had smooth corneal surfaces and no sequelae after healing. 2 cases had superficial punctate keratopathies, and 1 case filamentary keratitis .The results suggest that complete scraping of corneal epithelium should be avoided as far as possible in the posterior segment surgery .