沐舒痰治疗分泌性中耳炎的临床研究

Clinical studies on treatment ofsecretory otitis media usingambroxol

目的评价沐舒痰治疗分泌性中耳炎的疗效。方法总结35例分泌性中耳炎的分组临床研究结果。结果沐舒痰较常规治疗能明确改善耳鼻症状。治疗2周后,平均气导听力较常规治疗提高近10 dB。结论沐舒痰可有效控制炎症,缩短病程。为治疗分泌性中耳炎提供了新的思路。

PURPOSE To study the effect of ambroxol on secretory otitis media.METHODS We summarized the clinical studies on 35 outpatients of two groups with secretory otitis media who were treated by ambroxol (n = 22) and routine therapy (n = 13) respectively.RESULTS Ambroxol which was claimed to increase both the synthesis andthe secretion of surfactant in eustachian tube ameliorated the air-conduction hearing approximately 10 dB than routine therapy did, and also improved the ear and nose symptoms apparently after 2 weeks treatment.CONCLUSIONS Ambroxol does control the inflammation and reduce the prolongation of secretory otitis media through facilitating opening of eustachian tube and clearing of middle ear effusion, and this might be the effective way to crack down the deadlock of pharmaceutical therapy in the field.