声门上型喉癌侵犯喉软骨的病理研究

Pathological study of laryngeal cartilage invaded by supraglottic carcinoma

目的探讨声门上型喉癌侵犯喉软骨的特点和相关因素。方法对70例声门上型喉癌全喉切除标本连续切片进行观察分析。结果会厌软骨,甲状软骨,杓状软骨和环状软骨受累率分别为82.9%,30%,31.4%,1.4%,会厌软骨受累率最高,其受累方式分小孔浸润型和直接破坏型,前者为早期受累方式,临床T_3,T_4期病变各软骨受累率较T_2期病变高。结论声门上型喉癌易破坏会厌软骨,50%左右没有累及甲状软骨和杓状软骨,是保留喉软骨支架行喉部分切除术的重要条件。

PURPOSE To study the characteristics and relative factors of laryngeal cartilage invaded by supraglottic carcinoma.METHODS Serial sections of 70 supraglottic carcinomas were investigated.RESULTS Invasion rates of epiglo-ttic. thyroid, arytenoid and cricoid cartilage were 82.9%, 30%, 31.4% and 1.4% respectively. The invasion rate of epiglottic cartilage was the highest. Epiglottic cartilage invasion was divided into two types, foramen invasion type and direct destruction type. The former was the early invasion type. Cartilage invasion rates of T3, T4 clinical stage were higer than that of T2 stage.CONCLUSIONS Epiglottic cartilage is easily involved in supraglottic carcinoma. About 50% without invasion of thyroid and arytenoid cartilage is an important condition of reservation for laryngeal skeleton and partial laryngec-tomy.