消化道炎性纤维瘤样息肉(附6例报告)

Inflammatory fibromatoid polyp of alimentary tract:Report of six cases

对6例消化道炎性纤维瘤样息肉进行了光镜、免疫组化及电镜观察,指出该病系发生于胃肠道粘膜及粘膜下的以局部炎症及纤维组织增生为特征的炎性假瘤,本文使用的名称更好地反映了该病的本质和形态特点,其临床症状因息肉的大小及部位而异,本组3例均因该病导致的急性梗阻而紧急手术,术中病理诊断可避免过大的手术和不必要的处置。

Six cases of inflammatory fibromatoid polyp of alimentary tract, 1. in the lower esophagus, 2. in the stomach and 3. in ileum were reported. Macroscopically, they were polypoid masses protruding into the lumen, ranging from 1 to 8cm in diameter, Microscopically, the lesions were found chiefly in the submucosa and were composed of numerous fibroblasts, loosely arranged collagenous fibres, network of small capillaries and varying amount of inflammatory cells of various types, including eosinophils, numerous in some cases. S-100 protein and vimentin were used for revealing the histogenesis, the former being negative and the latter positive. The lesion is most likely to be composed of inflammatory granulation tissue rather than true neoplasm. In order to avoid unnecessery extensive operation pre-or intra operative biopsy is indicated. To fit in with the histopathological changes, the term of 'Inflammatory fibromatoid polyp' is suggested.