清利活血汤抗肝纤维化作用的临床观察

Clinical Observation of Qing Li Huo Xue Decoction on Cirrhosis Cases

目的 :探讨清利活血汤抗肝纤维化的作用。方法 :选择慢性肝炎、肝硬化患者 1 5 4例 ,随机分为观察组和对照组 ,分别用清利活血汤和西药治疗 3个月后观察 HA、PC 、IV- C、LN 4项肝纤维化指标变化情况。结果 :观察组治疗前后各项指标比较、两组治疗后比较差异均有非常显著性意义 ( P<0 .0 1 ) ,观察组 4项指标降幅明显大于对照组。结论 :清利活血汤有逆转慢性肝炎肝纤维化作用及控制和终止肝硬化病程作用。

Objective: To explore the anti fibrosis effect of Qing Li Huo Xue Decoction on Cirrhosis Cases.Methods:156 chronic hepatitis and cirrhosis cases were divided into Qing Li Huo Xue Decoction group and control group. After 3 months of treatment, serum HA?PCⅢ?IV C?LN were detected to see the changes.Results: Significant difference was observed before and after the treatment in the Qing Li Huo Xue Decoction group( P < 0.01). Difference was also observed between the 2 groups before and after the treatment( P < 0.01). The four indices decreasing range detected in the Qing Li Huo Xue Decoction group were higher than those in the control group. Conclusion:Qing Li Huo Xue Decoction was effective in restoring hepatic fibrosis and controlling the progress of cirrhosis.