经颅多普勒检测对糖尿病患者脑血管事件预测价值的探讨

Exploration of the value of predicting the cerebral vascular incident among DM patients detected by TCD

目的 :评价经颅多普勒超声 (TCD)检测糖尿病患者颅内动脉血流异常的预后价值。方法 :对 10 5例 48～ 85岁 2型糖尿病患者进行 TCD检测并前瞻性随访 6 7个月。结果 :本组糖尿病患者血流速度异常率较高占 5 7.1%,且以流速异常增高为主 ;随访期间 ,7例发生非脑血管病死亡 ,19例发生非致死性脑硬塞 ,1例发生非致死性脑出血 ,3例发生一过性脑缺血发作 (TIA)。所有 2 3例发生脑血管事件的患者进入研究时颅内动脉血流速度异常者脑血管事件发生率显著高于颅内动脉血流速度正常者 (P <0 .0 5 )。结论 :经颅多普勒超声检测颅内动脉血流速度异常对糖尿病患者随后脑血管事件的发生有预测价值。

Objective:To assess the prognostic value of abnormal cerebral arterial blood velocity among type 2 diabetes mellitus (DM) patients detected by Transcranial Doppler ultrasonography(TCD).Methods:105 cases of type 2 DM aged 48 to 85 were followed up for 67 months.Results:The TCD results showed that the rate of abnormal cerebral arterial blood velocity among type 2 DM patients was higher(57.1%),most cases had abnormal increase cerebral arterial blood flow velocity.During the follow-up,nonfatal symptomatic cerebral infarction and cerebral hemorrhage were registered in 19 and 1 patients,transient ischermia attack (TIA) was registered in 3 patients,7 patients died of causes other than cerebral vascular disease.The incidence on cerebral vascular incident in all the 23 patients were significantly higher in the patients with abnormal cerebral arterial blood velocity than those normal (P<0.05).Conclusion:Transcranial Doppler ultrasonographic detection of abnormal cerebral arterial blood veloity among type 2 DM patients can be used to predict the cerebral vascular incident.