慢性中耳炎鼓索神经的病理学研究

The pathological study of chorda tympani in chronic otitis media

对 6例尸头 (正常组 )及因慢性中耳炎 (COM)接受中耳手术的 45例患者 (病变组 )病变侧鼓索神经进行光镜和电镜检查。根据肉眼观察的鼓索神经形态将病变组分为三组 :A组为鼓索神经无病变组织侵蚀 ,B组为鼓索神经被肉芽组织、严重水肿粘膜和 (或 )胆脂瘤包绕 ,C组为由于病变严重或在原来的中耳手术中鼓索神经已被切断。病变组鼓索神经光镜和电镜下的检查结果与正常组比较有明显差异。B组鼓索神经有髓纤维数明显低于 A组。认为慢性中耳炎可引起鼓索神经病变 ;中耳病变越重 。

In order to explore the pathological change of chorda tympani nerve caused by the chronic otitis media, 6 cadavers (normal group) and 45 patients (abnormal group) performed otitis media surgery were examed the pathological changes of the chorda tympani under light and electron microscopy. In terms of the naked examinations of chorda tympani , the abnormal group was individed into 3 groups (group A,B,C). The results showed that there are significient differences between the finds of the normal group and abnormal one under the light and electron microscopy. The number of the myelinated axons in chorda tympani of abnormal group A is significient more than that of abnormal group B. These suggested that chronic otitis media can cause the pathological changes of the chorda tympani and the more serious the pathological change in the middle ear, the more serious the damage of chorda tympani.