随机双盲口服复方炔诺酮片防治药物流产后阴道出血的临床研究

Random and double bland clinical study of treating vaginal bleeding with taking table norethisterone compositae after drug abortion

目的:探讨一种有效、简便的方法防治药物流产后阴道出血。方法:随机双盲口服复方炔诺酮片或空白片,2片／次,1次／12 h,连服5 d。正铁碱性血红素法定量测定出血量。放免法测定用药前后血β-HCG、E2、P、LH、FSH水平。结果:治疗组阴道出血持续时间及阴道出血量均明显少于对照组。治疗组用药后血β-HCG、E2值均较对照组明显下降(P<0.01和P<0.05)。对照组用药后血LH、P值较治疗组明显下降(P均<0.01)。结论:本法具有简单、价廉及有效的特点,值得进一步研究。

Objective: To study a simple、effective method for treating vaginal bleeding after drug abortion. Methods:The tables of norethisterone compounds or tables of blank were taken two tables and two times a day until fifth day.β-human chorionic gonadotropin (β-HCG)、estrodial (E2)、progestone (P)、luteinizing hormone (LH)、follicle stimulation hormone (FSH) were measured by 125I radio -immunity. Results: The time and the quantity of vaginal bleeding of treating group were less than control group. Compared to the control group, the concentration of the β-HCG and E2of treating group decreased significantly (P<0. 01 and P<0. 05). Compared to the treating group, the concentration of the LH and P of control group decreased significantly (P< 0. 01 for all) . Conclusion: The method has simple, cheap and effective character in our study and will be worthly researched.