摘要
为适合儿童用药,选用聚乙二醇-400和丙二醇为混合溶媒制备安定灌肠剂。用初均速法测定其稳定性,得到活化能为25.54kcal·mol^(-1),20℃贮存期为480d。
Polyethylene glycol(PEG-400)and propylene glycol(PG)was selected as a mixed solvent to Prepare di-azepam eneama for children use.The initial average rate method was applied to determine the stability of diazepameneama.The activationenergy was 25.54 Kcal.mol<sup>-1</sup>;the shelflife estimated at 20℃ was 480 days.
出处
《中国医院药学杂志》
CAS
CSCD
北大核心
1993年第10期27-28,52,共3页
Chinese Journal of Hospital Pharmacy
关键词
安定灌肠剂
初均速法
活化能
药物贮存期
diazepam
eneama
initial average rate method
activation energy
Pharmaceutical shelflife