摘要
s To explore the changes of multifocal electroretinograms (mfERG) before and after retinal detachment surgery and to evaluate its clinical significance Methods Twenty three patients (23 eyes) with rhegmatogenous retinal detachment underwent mfERG before and after surgery The latencies and average response densities of N 1 wave and P 1 wave of mfERGs in detached areas, attached areas, fovea and the entire tested area were compared before and after surgery Results Preoperatively, the average response densities of N 1 wave and P 1 wave in the detached area were significantly smaller than those in attached areas ( t =3 68, t =4 26, P 【0 01), and the latencies of N 1 wave and P 1 wave in detached areas were significantly longer than those in attached areas ( t =3 07, t =3 89, P 【0 01) Postoperatively, the average response densities of N 1 wave and P 1 wave in detached areas, fovea and the entire tested area increased, and there were significant differences pre and postoperatively ( P 【0 05) However, the latencies of N 1 wave and P 1 wave before and after surgery showed no significant differences ( P 】0 05) Conclusions The mfERG is a useful tool to evaluate the recovery of posterior retinal function after retinal detachment surgery The response density is a more sensitive index than latency to evaluate retinal function of retinal detechment
目的 探讨视网膜脱离术前和术后多焦视网膜电图 (multifocalelectroretinogram ,mfERG)的改变及评价其临床应用价值。方法 2 3例 ( 2 3只眼 )患裂孔源性视网膜脱离患者手术前后分别进行了mfERG检查。于脱离区 ,非脱离区 ,中心凹及整个测试区 ,对手术前和手术后mfERG的N1波和P1波的潜伏期和平均反应密度进行比较。结果 手术前脱离区的N1波和P1波的平均反应密度明显小于非脱离 ,差异有显著性意义 (t=3 68,t4 2 6,P <0 .0 1 ) ,脱离区的N1波和P1波潜伏期时明显比非脱离区延长 ,差异有显著性意义 (t=3 .0 7,t=3 .89,P <0 .0 1 )。手术后于脱离区 ,中心凹和整个测试区的N1波和P1波平均反应密度较术前明显增大 (P <0 .0 5) ,但N1波和P1波的潜伏期则无明显变化 (P >0 .0 5)。结论 mfERG是评价术后视网膜功能恢复的有用工具 ,对视网膜功能测试反应密度较潜伏期为更敏感的指标。
