小儿重症肌无力危象

Infantile Myasthenia Gravis Crisis

目的 研究小儿重症肌无力危象的临床特点、诊断标准及治疗方法。方法 对4例重症肌无力危象患儿作一回顾性分析。结果 4例为急性起病,分别表现为两侧眼睑下垂,眼球活动受限,吞咽困难、四肢肌力、肌张力减弱。结论 小儿重症肌无力的病史和新斯的明试验阳性是诊断本病的重要依据。使用溴化吡啶斯的明和泼尼松可防止危象再发生。

Objective To study the clinical features,the criterion for diagnosis and the therapeutic approaches of infantile myasthenia gravis. Methods Four cases with myasthenia gravis crisis were given a retrospective analysis. Results All of the four cases were acute at the bilateral blepharoptosis,restriction of ocular movement,dysphagia, weakness of extremities,and weakening of muscular tension. Conclusion Medical history of infantile myasthenia gravis and positive of neostigmine test are important diagnostic bases of this disease. Applying pyridostigmine bromide and prednisone could prevent the recurrence of the crisis.