摘要
姜黄素(curcumin)是从姜科姜黄属植物的根茎中提取出来的一种黄色植物多酚,具有抗炎、抗氧化等多种药理作用,可以改善癌症、糖尿病和脑外伤等多种疾病症状。近年来随着对姜黄素的深入研究,发现其在神经系统疾病中也有较好的效果,如阿尔茨海默病、帕金森病、神经疼痛和神经系统肿瘤等。该文综述了姜黄素神经保护效应及其机制。
Curcumin is a low molecular weight polyphenol compound derived from the rhizome of the plant Curcuma longa. Curcumin was reported to have anti-inflammation, anti-oxidant,anti-cancer and other pharmacological effects. In recent years,curcumin has also been shown to be effective in several neurological disorders,such as Alzheimer’s disease,Parkinson’s disease,neuropathic pain and neuroblastoma. This paper reviewed the neuroprotective effects and the potential therapeutic mechanisms of curcumin.
出处
《神经药理学报》
2012年第2期58-64,共7页
Acta Neuropharmacologica
基金
河北省教育厅基金资助项目(No.Z2008106)
河北北方学院基金资助项目(No.2001017)
