摘要
川芎茶调剂给小鼠灌胃的最大耐受量为44.76g/kg,按最大耐受量的1/12,1/24,1/48设置川芎茶高、中、低3个剂量灌胃给药,川芎茶使大鼠炎症足和非炎症足的痛阈均显著上升,能提高大鼠鼠尾电刺激的痛阈值,对电刺激家免齿髓致痛也有显著抑制作用,结果表明川芎茶调剂具显著的解热镇痛作用.
Maximum tolerance dose (MTD) of Chuangxiong Tea P. O in mice was 44. 76 g/kg. 3 doses according to 1/12, 1/24,1/48 of MTD were set up. Chuanxiong tea inhibited the pains of rat paw, rat cauda and rabbit dental medulla evoked by electrical stimulus; and abatement of fever in rabbit by baker’s yeast. These results show that Chuanxiong tea has obvious analgesic effect and abatement of fever, it’s, machnism could be on centrel nervous system.
出处
《中山大学学报论丛》
1994年第6期152-157,共6页
Supplement to the Journal of Sun Yatsen University
关键词
川芎茶调剂
解热
镇痛
Chuanxiong tea
analgesa
abatement of fever
