摘要
1986～1987年新疆南部和田发生了一起肠道传播的非甲非乙型肝炎的流行。本研究用免疫电镜方法(IEM)对6例急性期病人的60份粪便标本进行了排病毒规律的检测。其中5例排病毒阳性(83.3％);全部粪便标本的病毒颗粒检出率为28.3％(17/60)。发病前1～4天的粪便标本阳性率为100％(3/3);发病后9～12天的阳性率为14.3％(1/7);发病两周后的22份标本全部阴性。17份不同病期收集的阳性粪便标本,94.1％(16/17)出现在病人血清转氨酶(SGPT)高峰值前,此时SGPT在100IU/L以下。故此,肠道传播的非甲非乙型肝炎患者的隔离期,应定为病后2～3周。
A total of 60 stool samples collected from patients suffering from acute non-A, non-B hepatitis were examined by immune electron microscopy (IEM) during an epidemic of the disease in Hetian area, Xinjiang in 1986—87. The virus was found in feces in 83.3 per cent of patients, and 28.3 per cent (17/00) of the samples collected. 100 per cet of stool Samples collected 1—4 days before illness were positive for the virus. 14.3 per cent (1/7) of the stool samples excreted the virus within 9—12 days after theonset of the disease, whereas the virus was not detected in 22 samples collected later than 13—24 days after the onset of the illness. In 94.1 per cent of samples the virus were obtained daring late incubation period and early acute phases when SGPT was under 100 Iu/1. In the view of mentiened above finding we suggest that isolation period of this disease should be decided that, it had better be kept up at least 2～3 weeks from onser of the disease.
