摘要
10名有长期使用 S 牌或 C 牌烫发剂历史、年龄为50～65岁的妇女作志愿者参加染发试验。收集其一次染发前异24h 的全尿,经402树脂柱吸附、去除组氨酸及洗脱等处理后得到尿浓缩物。用 Ames标准平皿掺入试验检测其致突变。本实验结果表明使用 S 牌及 C 牌染发剂未引起尿中致突变物质的增加。
Ten women who had a long history of using“S”or“C”hair dye had their hair colored oncemore with the hair dyes“S”or“C”.Two 24hr urinesamples were collected before and after thedyeing.The samples were passed through the pret- reared 402 resin column.The urine concentrateswere obtained following removal or histidine on thecolumn.The concentrates dissolved in DMSO wereassaed for mutagenic activity by Ames Salmonella-Microsome incorporation test.None of the samplestaken following the use of hair dye“S”or“C”gaveany indication of significant increase in revertantcolonies when compared with vehicle control orsamples taken before hair dyeing.
