摘要
观察使用ＨＡＶ疫苗株和野毒株感染普通狨猴后引起的病理变化，并对病变作分级描述。结果显示，疫苗株感染的狨猴未见异常。
The liver histopathological changes of common marmosets inoculated with wild type HAV strains or the live attenuatd hepatitis A vaccine (H2 strain) have been reported.The relationship between histopathology and liver enzyme elevation was presented.The liver pathological changes have been classified and described.The results showed that there was no abnormal changes in the liver tissue of marmosets inoculated with vaccine virus,but severe liver histopathological damages were revealed in all animals infected with the wild type strains.
基金
美国中华医学基金
