期刊文献+

运用超低剂量技术的多层CT结肠成像检测结肠直肠息肉:与高分辨率电子直肠镜的比较

Detection of colorectal polyps by multislice CT colonography with ultra-low-dose technique:Comparison with high-resolution videocolonoscopy
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摘要 Background: This prospective study compared multislice CT colonography with ultra-low-dose technique to high-resolution videocolonoscopy as the standard for detection of colorectal cancer and polyps. Methods: After standard bowel preparation,115 patients underwent multislice CT colonography with an ultra-low-dose multislice CT colonography protocol immediately before videocolonoscopy. After noise reduction by using a mathematical algorithm, ultra-low-dose multislice CT colonographic images were analyzed in blinded fashion,and the results were compared with the results of high-resolution videocolonoscopy. Results: A total of 150 lesions weredetected by high-resolution videocolonoscopy in 115 patients.For ultra-low-dose multislice CT colonography, sensitivities for detection of polyps less than 5 mm in size, 5 to 10 mm, and greater than 10 mm in diameter were 76% , 91% , and 100% , respectively.Although the sensitivity for detection of flat lesions was only 50% , the sensitivity and the specificity for detection of polyps 5 mm or greater in size were 94% and 84% ,respectively. For adenomatous lesions greater than 5 mm in size, sensitivity was 94% and specificity was 92% . The overall specificity was 79% . The calculated effective radiation dose ranged between 0.75 and 1.25 mSv. Conclusions: Compared with high-resolution videocolonoscopy, ultra-low-dose multislice CT colonography has excellent sensitivity and specificity for detection of colorectal lesions 5 mm or greater in size, and the radiation exposure is relatively low. However, before this technique can be generally recommended for colorectal screening,further improvement in the detection of flat and extremely small lesions must be achieved. Background: This prospective study compared multislice CT colonography with ultra-low-dose technique to high-resolution videocolonoscopy as the standard for detection of colorectal cancer and polyps. Methods: After standard bowel preparation,115 patients underwent multislice CT colonography with an ultra-low-dose multislice CT colonography protocol immediately before videocolonoscopy. After noise reduction by using a mathematical algorithm, ultra-low-dose multislice CT colonographic images were analyzed in blinded fashion,and the results were compared with the results of high-resolution videocolonoscopy. Results: A total of 150 lesions weredetected by high-resolution videocolonoscopy in 115 patients.For ultra-low-dose multislice CT colonography, sensitivities for detection of polyps less than 5 mm in size, 5 to 10 mm, and greater than 10 mm in diameter were 76% , 91% , and 100% , respectively.Although the sensitivity for detection of flat lesions was only 50% , the sensitivity and the specificity for detection of polyps 5 mm or greater in size were 94% and 84% ,respectively. For adenomatous lesions greater than 5 mm in size, sensitivity was 94% and specificity was 92% . The overall specificity was 79% . The calculated effective radiation dose ranged between 0.75 and 1.25 mSv. Conclusions: Compared with high-resolution videocolonoscopy, ultra-low-dose multislice CT colonography has excellent sensitivity and specificity for detection of colorectal lesions 5 mm or greater in size, and the radiation exposure is relatively low. However, before this technique can be generally recommended for colorectal screening,further improvement in the detection of flat and extremely small lesions must be achieved.
机构地区 Division of Medicine
出处 《世界核心医学期刊文摘(胃肠病学分册)》 2005年第1期35-35,共1页 Core Journals in Gastroenterology
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