摘要
Objective. To evaluate the occurrence and changes over time of upper gastroint estinal symptoms in adult subjects randomly recruited from the general populatio n. Material and methods. A questionnaire recording of upper gastrointestinal sym ptoms with a 10-year follow-up was carried out in a random sample of the adult population of Gteborg. The original sample, from 1986, comprised 441 subjects within the age span of 20-79 years. In total, 337 subjects participated in the index assessment, of which 197 (95 F) subsequently answered the second question naire 10 years later. Results. A majority of the responders (159/197, 83%) repo rted no change in their global assessment of symptoms. Neither the point prevale nce nor the severity for any symptom changed significantly over time. The preval ence of heartburn and acid regurgitation was 25 and 22%, respectively, and the corresponding yearly incidence was estimated to be 1.8 and 1.2%. The main predi ctor for the occurrence of symptoms of moderate to severe degree at follow-up w as the presence of the same symptom 10 years previously. Age or gender per se di d not significantly influence the occurrence of symptoms. Changes in body mass i ndex and anti-reflux medication co-varied with the severity of the symptoms he artburn and acid regurgitation. Conclusions. Oesophageal symptoms are common in the adult Swedish population and seem to be fairly stable over time.
Objective. To evaluate the occurrence and changes over time of upper gastroint estinal symptoms in adult subjects randomly recruited from the general populatio n. Material and methods. A questionnaire recording of upper gastrointestinal sym ptoms with a 10-year follow-up was carried out in a random sample of the adult population of Gteborg. The original sample, from 1986, comprised 441 subjects within the age span of 20-79 years. In total, 337 subjects participated in the index assessment, of which 197 (95 F) subsequently answered the second question naire 10 years later. Results. A majority of the responders (159/197, 83%) repo rted no change in their global assessment of symptoms. Neither the point prevale nce nor the severity for any symptom changed significantly over time. The preval ence of heartburn and acid regurgitation was 25 and 22%, respectively, and the corresponding yearly incidence was estimated to be 1.8 and 1.2%. The main predi ctor for the occurrence of symptoms of moderate to severe degree at follow-up w as the presence of the same symptom 10 years previously. Age or gender per se di d not significantly influence the occurrence of symptoms. Changes in body mass i ndex and anti-reflux medication co-varied with the severity of the symptoms he artburn and acid regurgitation. Conclusions. Oesophageal symptoms are common in the adult Swedish population and seem to be fairly stable over time.