摘要
Objective.To determine the nutritional status in patients treated for gastric non-Hodgkin’s lymphoma(NHL) .Material and methods.Patients treated during the period 1990-99 according to a protocol including primary gastric surgery for eligible patients were registered prospectively in successive patients.Those with aggressive lymphomas in stage IE-IIE underwent gastric surgery followed by CHOP-like chemoth-erapy.Patients with indolent lymphomas and localized disease did not receive any further treatment if the operation was considered radical;otherwise,they received local radiotherapy after surgery.Patients with advanced disease underwent gastric surgery only if there was a considerable risk of bleeding or perforation.Patients below the age of 80 years and in complete remission were offered a cross-secti-onal examination a median of 102 months later,including clinical examination with estimation of body mass index,upper endoscopy and blood tests(haemoglobin,ferritin,serum-Fe,total iron-binding capacity(TIBC) ,vitamin B 12,homocysteine,vitamin D status,parathyroid hormone(PTH) ,albumin and electrolytes) .Results.Forty patients were identified,of whom 33 met for follow-up examination.Seventeen patients had a partial gastrectomy(PG) ,9 a total gastrectomy(TG) and 7 patients were not operated on.The patients in the TG group had significant weight loss.Furthermore,the patients in the TG group had a lower storage iron content(s-ferritin and s-iron saturation) ,lower s-vitamin D,higher s-PTH and homocysteine than the other groups.Conclusions.If surgery is necessary for gastric lymphomas,a PG should be performed when possible.The patients should receive dietary advice and be followed-up at least yearly for nutritional deficiencies.Regular intake of vitamin D and-B 12,calcium,folate and iron should be considered.
Objective.To determine the nutritional status in patients treated for gastric non-Hodgkin's lymphoma(NHL) .Material and methods.Patients treated during the period 1990-99 according to a protocol including primary gastric surgery for eligible patients were registered prospectively in successive patients.Those with aggressive lymphomas in stage IE-IIE underwent gastric surgery followed by CHOP-like chemoth-erapy.Patients with indolent lymphomas and localized disease did not receive any further treatment if the operation was considered radical;otherwise,they received local radiotherapy after surgery.Patients with advanced disease underwent gastric surgery only if there was a considerable risk of bleeding or perforation.Patients below the age of 80 years and in complete remission were offered a cross-secti-onal examination a median of 102 months later,including clinical examination with estimation of body mass index,upper endoscopy and blood tests(haemoglobin,ferritin,serum-Fe,total iron-binding capacity(TIBC) ,vitamin B 12,homocysteine,vitamin D status,parathyroid hormone(PTH) ,albumin and electrolytes) .Results.Forty patients were identified,of whom 33 met for follow-up examination.Seventeen patients had a partial gastrectomy(PG) ,9 a total gastrectomy(TG) and 7 patients were not operated on.The patients in the TG group had significant weight loss.Furthermore,the patients in the TG group had a lower storage iron content(s-ferritin and s-iron saturation) ,lower s-vitamin D,higher s-PTH and homocysteine than the other groups.Conclusions.If surgery is necessary for gastric lymphomas,a PG should be performed when possible.The patients should receive dietary advice and be followed-up at least yearly for nutritional deficiencies.Regular intake of vitamin D and-B 12,calcium,folate and iron should be considered.
