灯盏花治疗椎-基底动脉缺血性眩晕64例

Effect of Astragalus Angrlica Mixture on Serum Lipids and Glomerulosclerosis in Rats with Nephrotic Syndrome

灯盏花治疗椎－基底动脉缺血性眩晕６４例吕云利，傅学锋，姚向荣，廖军，路逵自１９９５年１１月～１９９６年７月，我们用云南灯盏花注射液治疗椎一基底动脉缺血性眩晕（ＶＢＩＶ），并与传统中药丹参注射液作对照观察，疗效满意，报告如下。临床资料诊断接文献（中风与...

To confirm the renal protective action of Astragalus Angelica mixture (AAM). Methods: Effect of AAM was observed in puromycin amino-nucleoside induced nephrotic syndrome model of rat, and pravachol, an effective lipid lowering medicine, was used as Positive control. Results: AAM could not only reduce the serum levels of total cholesterol and triglyceride as pravachol did, but also could lower levels of low density lipoprotein and apolipoprotein B100(P＜0. 05). Light microscopic and immuno-histochemical examination revealed that in the same time of lowering serum lipids, this mixture could also cause reduction of glomerular sclerosing index(P＜0.01) and less accumulation of extracellular matrix (P＜0.01 ). Conclusions: AAM has the effects of regulating lipid metabolism, attenuating renal damage and maintaining renal function in rats with nephrotic syndrome.