1Breier A. Cognitive deficit in schizophrenia and its neurochemical basis[J]. Br J Psychiatry, 1999,174(Suppl 37):16-18.
2MareK G J,Wright R A,Schoepp D D,et al. Physiological antagonism between 5-hydroxytryptamine(2A)and group Ⅱ metabotropic glutamate receptors in prefrontal cortex[J]. J Pharmacol Exp Ther, 2000,292(1):76-87.
4Yamamoto B K,Pehek E A,Meltzer H Y. Brainregion effects of clozapine on amino acid and monoa mine transmission[J]. J Clin Psychiatry, 1994,55(Suppl B):8-14.
5Evins A E,Amico E T,Shih V,et al. Clozapine treatment increases serum glutamate and aspartate compared to conventional neuroleptics[J]. J Neural Transm, 1997,104(6):761-766.
6Malhotra A K, Adler C M, Kennison S D, et al. Clozapine blunts N-methyl-D-aspartate antagonist-induced psychosis:a study with ketamine[J]. Biol psychiatry, 1997,42(8):664-668.
7Jentsch J D,Redmond D E Jr,Elsworth JD,et al. Enduring cognitive deficits and cortical dopamine dysfunction in monkey after long-term administration of phencycclidine[J]. Science, 1997,277(5328):953-955.
8Goff D C,Tsai G,Manoach D S,et al. D-Cycloserine added to clozapine for patients with schizophrenia[J]. Am J Psychiatry, 1996,153(12):1628-1630.
6Enomoto T, Noda Y, Nabeshima T. Phencyclidine and genetic animal models of schizophrenia developed in relation to the glutamate hypothesis [ J ]. Methods Find Exp Clin Pharmacol, 2007,29 (4) :291 -301.
7Qin S, Zhao X, Pan Y, et al. An association study of the N - methyl - D - aspartate receptor NR1 subunit gene ( GRIN1 ) and NR2B subunit gene (GRIN2B) in schizophrenia with universal DNA micmarray[ J]. Eur J Hum Genet, 2005,13(7) :807 -814.
8Clinton SM, Haroutunian V, Davis KL, et al. Altered transcript expres- sion of NMDA receptor - associated postsynaptic proteins in the thalamus of subjects with schizophrenia [ J ]. Am J Psychiatry, 2003,160 ( 6 ) : 1100 - 1109.
9Nakagawa T. The biochemistry, ultrastructure, and subunit assembly mechanism of AMPA receptors [ J ]. Mol Neurobiol, 2010,42 ( 3 ) : 161 - 184.
10Rambhadran A, Gonzalez J, Jayaraman V. Conformational changes atthe agonist binding domain of the N - methyl - D - aspartic acid receptor [J]. J Biol Chem, 2011,13 (19) :16953 -16957.