回神丹颗粒剂治疗老年期血管性痴呆的临床研究

Clinical Research of Huichundan Granule on Senile Vascular Dementia (VD)

目的 :观察中药制剂回神丹颗粒剂治疗老年期血管性痴呆的临床疗效。方法 :将全部病例分为观察组(n=118) ,对照组 (n=30)。观察组服用回神丹颗粒剂 ,对照组服用西药喜得镇。采用国际通用智力量表 (MMSE)评分标准 ,观察两组患者在时间定向力、空间定向力、语言功能等方面的改善情况。结果 :观察组总有效率为89 83 % ,对照组为60 00 % ,对两组有效病例追踪观察6个月 ,观察组好转维持率为99 06 % ,恶化率为0 94 % ;对照组好转维持率为83 33 % ,恶化率为16 67 %。结论

Objective: To observe the clinical effect of Chinese patent medicine Huichundan Granule on treating senile VD. Methods: All cases were divided into treatment group(n=18, given Huichundan Granule) and control group (n=30, given western medicine Hydergcine).Using MMSG core creterion, the abilities of temporal orientation, space orientation, speech and so on in both groups were observed.Results: The total effective rates were 89.83%, 60.00% in both groups respectively. Six months after that, the sustaining improving rate were 99.06%, 83.33%, the deteriorative rates 0.94%, 16.67% in treatment group and control group respectively.Conclusion: Huichundan Granule has a certain persistent effect on treating senile VD.