系统性红斑狼疮合并妊娠21例分析

A Clinical Analysis of 21 Cases of Systemic Lupus Erythematosus in Pregnancy

目的 :探讨系统性红斑狼疮 (SL E)合并妊娠的恶化率、妊高征发生率及妊娠期处理。方法 :对 1997～ 2 0 0 0年收治的 2 1例 SL E合并妊娠的临床资料进行回顾性分析。结果 :SL E合并妊娠病情恶化率及妊高征发生率分别为 5 2 .4 %及33.3% ,与 SL E病情活动和缓解有关。结论 :SL E合并妊娠病情容易加重 ,也易并发妊高征 ,应加强妊娠期监测和处理。

Objectives:To find out the rate of deterioration of SLE during pregnancy,the incidence of co existing pregnancy induced hypertension(PIH) in a induced and the ways of antepartum treatment.Methods: A retrospectivly analysis of the clinical data was performed in 21 cases of SLE with pregnancy from 1997 to 2000.Results: SLE with pregnancy had an acute deterioration rate(52.4%) and incidence of co existing PIH 52.4% and 33.3%.And that was related to whether the patients were in disease progress or not.Conclusions: When SLE happens in pregnancy, it is more likely to get worse and complicated with PIH.It is necessary to enhance the antepartum monitoring and treatment for these patients.