C反应蛋白及前白蛋白在小儿急性呼吸道感染中的应用

Application of C Reaction Protein and Prealbumin in Children with Acute Respiratory Tract Infection

目的 评价C反应蛋白 (CRP)、前白蛋白 (PA)在区分小儿急性呼吸道感染病原体中的作用。方法 检测急性呼吸道感染患儿 4 0例及健康儿童 6 0例血常规和血清中CRP、PA含量。结果 (1)细菌感染组 (A组 )与对照组 (C组 )相比较 ,CRP明显升高。两者差异有显著性 (P <0 0 0 1) ,PA明显降低 (P <0 0 0 1)。 (2 )病毒感染组 (B组 )与对照组比较CRP、PA差异均无显著性。结论 在小儿急性呼吸道感染时 ,血液中CRP和PA发生改变 ,可借以鉴别细菌感染。但临床上CRP检测因其快速、简单。

Objcctives:To evaluate the application of C reaction protein(CRP) and prealbumin (PA) in distinguish the pathogen in children with acute respiratory tract infection. Methods: We detected the blood routine and serum CRP and PA in 40 children with acute respiratory tract infection and 60 healthy children, respectively. Results:(1)Compare the group of bacteria infection (Group A) with the control group(Group C), CRP increased clearly and PA decreased, both of the differences are significant.(P<0 001);(2)comparison with the virus infection group (Group B)and Group C, CRP and PA are no clear differences. Conclusions:The serum CRP and PA changed in children with acute respiratory tract infection, which may be a indicator in differentiate the pathogen. Moreover, clinical CRP measurement is rapid, simple and stable, So we recommend it.