革兰阴性杆菌对第三代头孢菌素的耐药性分析

Analysis of Gram-negative Comebacterium for the Third-generation's Drug Resitance

目的 分析临床感染性疾病分离的常见革兰阴性杆菌 ,对第三代头孢菌素的耐药性 ,为临床合理使用抗生素提供必要依据。方法 采用FORTUNE— 2 0 0 0细菌鉴定药敏分析系统 ,对临床各类标本分离的细菌进行鉴定和药敏试验。结果 4 94株革兰阴性杆菌对第三代头孢菌素的总耐药率分别为头孢哌酮 (CPZ)最高 6 7%、氨曲南 (ATM ) 5 4 %、头孢西丁 (CFX) 4 1%、头孢他啶 (CAZ) 36 %、头孢曲松 (CAX) 2 8%、头孢噻肟钠 (CFT) 2 5 %、亚胺培南 (IPM ) 16 %。结论 革兰阴性杆菌对第三代头孢菌素的耐药日趋严重 。

Objective To analysis and etermine the drug resitance that the most common gramnegative bacterias were isolated from the clinical disease to the third generation in order to provide necessary gist for use with reason antibiotics Methods By FORTUNE-2000 Aicrobidgy and Antibiotic susceptibitity analysis system, to identify and susceptibility test for different kinds of clinlcal samples Results The total resistant rate: Cefoperazone(CPZ)67%, Aztreonam(ATM)54%, Cefoxitin(CFX)41%, Ceftazidime(CAZ)36%, Ceftriaxone(CAX)28%, Cefotaxime(CFT)25%, Imipenem(IPM)16% Conclusion It's harder and harder Gram negative bacteria resistant for the third generation Should pay attetition to it