摘要
Apoptosis, also known as programmed cell death,is a normal process contributing to tissue tumor during development and in the adult.During development apoptosis is involved in tissue homeostasis and eliminating nonfunctional,superfluous or harmful cells.It is an active process controlled by some gene and factors such as caspases, bcl-2, Fas/FasL and NO.Type 1 diabetes mellitus is regarded as a chronic autoimmune disease resulting from progressive destruction of insulin-producing β-cells in the pancreas.The relationship between apoptosis with its modulation and type 1 diabetes mellitus was reviwed.
Apoptosis, also known as programmed cell death,is a normal process contributing to tissue tumor during development and in the adult.During development apoptosis is involved in tissue homeostasis and eliminating nonfunctional,superfluous or harmful cells.It is an active process controlled by some gene and factors such as caspases, bcl-2, Fas/FasL and NO.Type 1 diabetes mellitus is regarded as a chronic autoimmune disease resulting from progressive destruction of insulin-producing β-cells in the pancreas.The relationship between apoptosis with its modulation and type 1 diabetes mellitus was reviwed.
出处
《中国病理生理杂志》
CAS
CSCD
北大核心
2002年第9期1165-1168,共4页
Chinese Journal of Pathophysiology
基金
广东省中医药管理局科研课题 (No .10 110 7)
关键词
细胞凋亡
凋控
I型糖尿病
Apoptosis
Caspases
Genes, bcl-2
Diabetes mellitus, insulin-dependent
