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卵巢过度刺激综合征的防治 被引量：2

Prevention and Treatment of Ovarian Hyperstimulation Syndrome
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摘要 　本院生殖医学中心13例卵巢过度刺激综合征(OHSS)的所有病例均发生在体外受精-胚胎移植及其衍生技术的诱导超排卵后.临床表现主要为腹胀、腹水、少尿、血液浓缩、低蛋白血症、水电解质失衡和氮质血症等.OHSS往往与高妊娠率伴随,轻、中度OHSS经系统监护,多不需特殊治疗;较重的患者经人体白蛋白静脉输注,低分子右旋糖酐扩容,维持重要器官灌注等处理后治愈. Thirteen cases with ovarian hyperstimulation syndrome (OHSS) were analyzed retrospectively to investigate the clinical characteristics and the treatment of OHSS. All cases of OHSS occurred after induction of superovulation for IVF?ET and ICSI procedures. OHSS was associated with high pregnant rate. The main manifestations of OHSS included abdominal distension, ascites, oliguria, concentrated blood, hypoalbuminemia, electrolyte disturbance and azotemia, which could be controlled by intensive care, supplementation of albumin and volume expansion.
作者 胡娅莉 孙海翔 王玢 朱卫东 王志群
机构地区 南京大学医学院附属鼓楼医院妇产科
出处 《南京大学学报（自然科学版）》 CAS CSCD 北大核心 2002年第5期598-600,共3页 Journal of Nanjing University（Natural Science）
关键词 卵巢过度刺激综合征 超排卵 体外受精一胚胎移植 ovarian hyperstimulation syndrome(OHSS),induction of superovulation,IVF-ET
分类号 R711.75 [医药卫生—妇产科学]
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参考文献7

  • 1Navot D, Bergh P A, Laufer N. Ovarian hyperstimulation syndrome in novel reproductive technologies:prevention and treatment. Fert Ster, 1992, 58(2):249-259.
  • 2Mathur R, Jenkins J. Ovarian hyperstimulation syndrome: an endocrinopathy. Curr Opin Obstet Gynecol,2001, 13(3) :329-333.
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同被引文献13

  • 1朱桂金.重度卵巢过度刺激综合征病例分析[J].实用妇科与产科杂志,1993,9(1):49-50. 被引量：17
  • 2吴效科,陆康民,苏延华.卵巢内肾素-血管紧张素系统[J].中华妇产科杂志,1996,31(7):434-436. 被引量：6
  • 3Bassam M, Raed A G, Nadim S J, et al. Spontaneous ovarian hyperstimulation syndrome caused by hypothyroidism in an adult. Europe Journal of Obstetrics Gynaecology Reproductive Biology,2004,112:107-109.
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  • 5Artini P G, Monti M, Fasciani A, etal. Vascular endothelial growth factor, interleukin-6 and interleukin-2 in serum and follicular fluid of patients with ovarian hyperstimulation syndrome Europen Joural of Obstetrics and Gynecology Reproductive Biology, 2002,101.169- 174.
  • 6Albert C, Garrido N, Mercade A, et al. The role of endothelial cells in the pathogenesis of ovarian hyperstimulation syndrome. Molecular Human Reproduction, 2002,8 (5) : 409-418.
  • 7Inoue S, Fukuda K, Kudara T, et al. Augmented growth response to IGF-1 via increased IRS-1 in Chinese hamster ovary cells expressing kinasenegative insulin receptors. Diabetologia, 1999,42(6). 763-772.
  • 8Demeestere I, Gervy C, Centner J, et al. Effect of insulin-like growth factor-1 during preantral follicular culture on steroidogenesis, in vitro oocyte maturation, and embryo development in mice. Biological Reproduction, 2004,11 : 1-27.
  • 9Mazerhourg S, Bondy C A, Zhou J, et al. The insulin-like growth factor system: A key determinant role in the growth and selection of ovarian follicles? A comparative species study. Reproductive Domestic Animal, 2003, 38 (4) :247 -258.
  • 10Wang T H, Horng S G, Chang C L, et al. Human chorionic gonadotropin-induced ovarian hyperstimulation syndrome is associated with upregulation of vascular endothelial growth factor.The Journal of Clinical Endocrinology. Metabolism, 2002,87(7).3 300-3 308.

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南京大学学报（自然科学版）
2002年 第5期

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