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磷酸钙骨水泥作为药物缓释载体的研究进展 被引量：9

Advance in novel skeletal drug delivery system using self-setting calcium phosphate cement
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作者 张文明 戴伯川
机构地区 福建医科大学附属第一医院骨科 福建医科大学药学系化学教研室
出处 《福建医科大学学报》 2002年第3期340-342,共3页 Journal of Fujian Medical University
基金 福建省教育厅科研基金资助项目 (JA0 0 195)
关键词 磷酸钙骨水泥 药物缓释载体 研究进展 迟效制剂 生物相容性材料
分类号 R318.08 [医药卫生—生物医学工程]
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参考文献20

  • 1Constant BR,Ison IC,Fulmer MT,et al. Skeletal repair by in situ formation of the mineral phase of bone[J]. Science, 1995,267(5205):1796～1798.
  • 2黄粤,刘昌胜,邵慧芳,肖艳平.萘普生钠/磷酸钙骨水泥药物缓释体系的研究[J].药学学报,2000,35(1):44-47. 被引量：22
  • 3Otsuka M,Yoneoka K,Matsuda Y,et al. Oestradiol release from self-setting apatitic bone cement responsive to plasma-calcium level in ovariectomized rats,and its physicochemical mechanism[J]. J Pharm Pharmacol, 1997,49(12):1182～1188.
  • 4Otsuka M,Nakahigashi Y,Matsuda Y,et al. The in vitro and in vivo indomethacin release from self-setting bioactive glass bone cement[J]. Biomed Mater Eng, 1997,7(5):291～302.
  • 5Otsuka M,Matsuda Y,Wang Z,et al. Effect of sodium bicarbonate amount on in vitro indomethacin release from self-setting carbonated-apatite cement[J]. Pharm Res, 1997,14(4):444～449.
  • 6Otsuka M,Matsuda Y,Fox JL,et al. A novel skeletal drug delivery system using self-setting calcium phosphate cement. 9: Effects of the mixing solution volume on anticancer drug release from homogeneous drug-loaded cement[J]. J Pharm Sci, 1995,84(6):733～736.
  • 7Otsuka M,Nakahigashi Y,Matsuda Y,et al. A novel skeletal drug delivery system using self-setting calcium phosphate cement. 7. Effect of biological factors on indomethacin release from the cement loaded on bovine bone[J]. J Pharm Sci, 1994,83(11):1569～1573.
  • 8Otsuka M,Matsuda Y,Suwa Y,et al. A novel skeletal drug delivery system using a self-setting calcium phosphate cement. 5. Drug release behavior from a heterogeneous drug-loaded cement containing an anticancer drug[J]. J Pharm Sci, 1994,83(11):1565～1568.
  • 9Otsuka M,Matsuda Y,Suwa Y,et al. A novel skeletal drug delivery system using self-setting calcium phosphate cement. 2. Physicochemical properties and drug release rate of the cement-containing indomethacin[J]. J Pharm Sci, 1994,83(5):611～615.
  • 10Otsuka M,Matsuda Y,Suwa Y,et al. A novel skeletal drug-delivery system using self-setting calcium phosphate cement. 4. Effects of the mixing solution volume on the drug-release rate of heterogeneous aspirin-loaded cement[J]. J Pharm Sci, 1994,83(2):259～263.

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共引文献48

同被引文献141

引证文献9

二级引证文献30

福建医科大学学报
2002年 第3期

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