摘要
目的 探讨高位硬膜外阻滞 (TEB)治疗停止后扩张型心肌病患者心脏收缩功能是否继续改善。方法 上胸段棘突间穿刺至硬膜外腔 ,留置硬膜外导管 ,0 .5 %利多卡因 3~ 5ml每 2h推注一次 ,持续 4周 ,适当辅以常规治疗。测定并比较TEB治疗停止后 16周及停止初期扩张型心肌病患者射血分数(EF)、缩短分数 (FS)。结果 16周后EF值由 2 8.2 1%± 7.2 2 %升为 34.5 4%± 6 .16 %(P =0 .0 195 ) ,FS由 10 .5 7%± 2 .98%升为 13.43%± 3.18%(P =0 .0 2 12 )。结论 高位硬膜外阻滞治疗停止后扩张型心肌病患者心脏收缩功能继续改善 ,该方法对扩张型心肌病患者心脏收缩功能改善具有延迟作用。
Objective To investigate if cardiac function of patients with dilated cardiomyopathy (DCM) improved continuously when the treatment of thoracic epidural blockade (TEB) ceased.Methods Fifteen patients with DCM received continuous TEB by intermittent injection of 0.5% lidocaine 3~5 milliliters for 4 weeks. When TEB was ceased, left ventricular ejection fraction (EF) and fractional shortening (FS) were measured. Sixteen weeks after, the two parameters were measured again in 15 patients and the results were compared with those of initial stage.Results Sixteen weeks after cease of TEB, the value of EF rose from 28.21%± 7.22% to 34.54%± 6.16% (P= 0.019 5) and FS rose from 10.57%± 2.98% to 13.43%± 3.18% (P= 0.021 2).Conclusions Even though treatment of TEB was ceased, the rise of cardiac function of patients with DCM went on. The method of TEB has the delayed and beneficial effects on cardiac function of patients with DCM.
出处
《中华超声影像学杂志》
CSCD
2002年第9期521-522,共2页
Chinese Journal of Ultrasonography
基金
黑龙江省十五攻关项目资助 (GB0 1C1 2 6 0 3)
关键词
高位硬膜外阻滞
扩张型心肌病
心脏收缩功能
延迟作用
Echocardiography
Cardiomyopathy,congestive
Thoracic epidural blockade
Myocardial contraction