高频超声对原发性甲状旁腺疾病的诊断价值

Value of high-frequency ultrasonography in the diagnosis of primary parathyroid diseases

目的 探讨高频超声对原发性甲状旁腺疾病的诊断价值。方法 对 10 0例正常人及 30例拟诊为原发性甲状旁腺疾病的患者行甲状旁腺超声检测 ,检查结果与病理诊断、血清甲状旁腺激素等临床资料综合分析。结果 正常组在 2 0人中发现 2 7个正常甲状旁腺 ,甲状旁腺的检出率为 2 0 %( 2 0 /10 0 )。在 30例疑为甲状旁腺疾病的患者中超声检出患甲状旁腺疾病者 19例 ,病变甲状旁腺 2 1个 ,包括甲状旁腺腺瘤、腺癌、无功能囊肿、单纯性甲状旁腺肿大等 ,假阳性 3例 ;正常甲状旁腺 11例 ,超声检出的最小甲状旁腺直径 4.5mm ,无假阴性。结论 高频超声不仅能检出 10mm左右的甲状旁腺腺瘤 ,而且可能检出 >5mm正常或轻度肿大的甲状旁腺 ,为临床除外甲状旁腺疾病首选的可靠方法。

Objective To evaluate the value of high frequency ultrasonography in the diagnosis of primary parathyroid diseases.Methods Cervical area of 100 volunteers without biochemical suspected primary or secondary parathyroid diseases and 30 cases of clinically suspected primary parathyroid diseases were examined with ultrasonography.Results In control group,27 parathyroid glands were detected in 20% (20/100) volunteers.In disease group of 30 patients with clinically suspected parathyroid diseases,19 patients with 21 abnormal parathyroid glands were detected by ultrasonography.The diseases were parathyroid adenoma,parathyroid carcinoma,nonfunctioning cyst,and enlarged parathyroid gland.Ultrasonography revealed normal parathyroid glands in 11 patients and 3 false positive cases.Minimal size of parathyroid gland demonstrated on ultrasonography was 4.5 mm,and no false negative case was found.Conclusions Cervical ultrasonography should be used as a first line test for diagnosing parathyroid diseases because it is a reliable,non invasive and relatively inexpensive examination which can detect as small as 5 mm parathyroid gland.