儿童注意缺陷/多动障碍与血铅、微量元素水平关系的探讨

Children with Attention Drawback/Hyperkinetic Disorder and Their Blood Lead and Other Trace Element levels

目的 探讨儿童注意缺陷/多动障碍 (ADHD)与血铅和血微量元素水平的关系。 方法 用原子吸收分光光度法对90例ADHD患儿及60例对照组进行血铅、锌、铜、铁、钙、镁水平测定。结果 ADHD患儿血铅水平 (109.5±24.9) μg/L高于对照组 (99.2±13.4) μg/L(P<0.01) ,血锌、钙水平 (12.3±2.1) μmol/L、(2328.1±64.7) μmol/L低于对照组 (13.6±2.1) μmol/L、(2360.9±104.7) μmol/L(P<0.01和0.05) ,血铅与血锌呈负相关(P<0.05)。结论 轻度铅中毒、锌、钙缺乏可能是ADHD的病因之一 ,在诊治ADHD时 ,应采取相应的检测。

Objective To explore the relationship between attention drawback/hyperkinetic disorder (ADHD) in children and their blood trace element levels.Methods Blood Pb, Zn, Cu, Fe, Ca and Mg levels of 90 ADHD children were determined by atom-absorbent spectrophotometry.Results The blood Pb level was higher in ADHD children (109.5±24.9)μg/L than that in normal children[(99.2±13.4)μg/L,P<0.01], the Zn and Ca levels were lower in ADHD children(12.3±2.3)μmol/L,2328.1±64.7)μmol/L than those in normal [(13.6±2.1)μmol/L,2360.9±104.7]μmol/L,P<0.01 and 0.05 respectively