脱细胞异体真皮与自体刃厚皮片移植16例

Clinical application of acellular dermis xenograft with split-thickness skin autograft in 16 cases

目的 拓展复合皮的运用范围。方法 切除黑色素痣、皮肤血管瘤、皮肤肿瘤患者病变皮肤组织,充分止血、洗净。用脱细胞异体真皮覆盖,固定后,立即在脱细胞异体真皮上移植自体刃厚皮片,缝合后打包加压、固定。观察移植皮片的存活率、生长情况和创面收缩情况。结果 切除病变组织后,移植脱细胞异体真皮加自体刃厚皮片,成功率高,无排斥反应;创面愈合平坦,颜色淡红,色素沉着轻微,表面光滑;皮肤外观平整,柔软,功能良好。结论 脱细胞异体真皮加自体刃厚皮片不仅用于瘢痕切除创面的覆盖,而且用于黑色素痣、皮肤血管瘤、皮肤肿瘤等手术切除创面的覆盖,是皮肤修复手术的较为理想的材料。

Objective To extend clinical application of acellular dermis xenograft with split-thickness skin autograft. Methods Melanosis, hemangioma cutis and dermatofibroma were excised. Then the acellular allogeneic dermis and autologous split -thickness skin were applied. Attention was paid on the grafted skin of surviving, growing and shrinking. Results The transplantation of acellular allogeneic dermis graft with split-thickness autologous skin graft resulted in high rate of surviving without sings of rejection. All grafts showed a pink skin color and the skin was felt soft and smooth. The skin's function was good. Conclusion The covers of acellular dermis xenograft with split-thickness skin autograft were not only used in scars, but also in melanosis , hemangioma cutis and dermatofibroma. Acellular dermis with split-thickness tologous skin graft is an ideal covering material in clinical skin transplantation.