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Ni^(2+) treatment causes cement gland formation in ectoderm explants of Xenopus laevis embryo

Ni^(2+) treatment causes cement gland formation in ectoderm explants of Xenopus laevis embryo
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摘要 We found T-type calcium channel blocker Ni2+ can efficiently induce the formation of cement gland in Xenopus laevis animal cap explants. Another T-type specific calcium channel blocker Amiloride can also induce the formation of cement gland, while L-type specific calcium channel blocker Nifedipine has no inductive effect. These results may offer us an new approach to study the differentiation of cement gland through the change of intracelluax calcium concentration. We found T-type calcium channel blocker Ni2+ can efficiently induce the formation of cement gland in Xenopus laevis animal cap explants. Another T-type specific calcium channel blocker Amiloride can also induce the formation of cement gland, while L-type specific calcium channel blocker Nifedipine has no inductive effect. These results may offer us an new approach to study the differentiation of cement gland through the change of intracelluax calcium concentration.
出处 《Cell Research》 SCIE CAS CSCD 1999年第1期71-76,共6页 细胞研究(英文版)
关键词 爪蟾 蛙胚 外胚层 粘液腺形成 Ni^2+处理 T型钙通道 分化 Ni^(2+), cement gland, gastrulation, T-type calcium channel
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