五例心脏移植术后的远期观察

Observation on the 5 long-term survivals of heart transplantation

目的 :通过对 5例原位心脏移殖术后病人的远期观察 ,探讨心脏移植术后受者的远期存活情况。方法 :通过冠脉造影、心动超声、心肌活检、心电、血生化、血常规、环孢素A浓度测定等方法观察病人冠脉病变情况 ,心功能状态 ,排斥反应程度。结果 :5例心脏移植受者冠脉造影均正常 ,心动超声除两例轻度瓣膜返流外 ,其余未见明显异常。心肌活检两例有轻度排诉反应。结论 :正常合理的用药 ,心脏移植受者的存活状态是相当令人满意的 。

OBJECTIVE:To explore the long-term survivals of heart transplantation by observating five survivals of heart transplantation in situ. METHODS: To observe coronary pathological process, cardiac status and the degree of reject reaction, parameters investigated included coronary angiography, echocardiogram, electrocardiogram, myocardial biopsy, blood biochemical check-ups, routine examination of blood and the detection of concentration of Ciclosporin A. Results: The examination found that all the patients were normal with coronary arteriograhpy and only two patients were slight valvular regurgitation with echocardiogram. Mild reject reaction was found in two invalids by myocardial biopsy. Conclusion: Through reasonable medicaiton, the condition of cardiac transplants is satisfactory and long-term survival also can be prospective.