心脏黏液瘤的免疫组织化学观察

Immunohistochemical study of cardiac myxoma

目的 观察几种标记物在心脏黏液瘤 (CM)组织中的表达。方法 应用免疫组化技术 ,检测 12例CM组织中的 (FⅧAg)、(calretinin)、S 10 0、NSE、vimentin、desmin、CK及CD117的表达特点。结果 12例calretinin呈强阳性 ,4例CK阳性 ,6例S 10 0阳性 ,7例NSE、vimentin、desmin阳性。 9例FⅧAg阳性 ,其中 2例强阳性。 12例CD117均阴性。结论 CM是一种呈多向分化的肿瘤。

Objective To study the expression of immunohistochemical markers in cardiac myxoma(CM). Methods 12 cases of CM were investigated by immunohistochemistry for FⅧ related antigen,calretinin,S 100, vimentin, desmin,CK and CD117. Results Calretinin was strongly expressed in all cases. FⅧ related antigen was found to be positive in 9 cases, of which have 2 cases showed strong positive. NSE, vimentin and desmin were found to be positive in 7 cases, S 100 in 6 cases, CK in 4 cases. All cases were negative for CD117. Conclusions CM was a multi direction differentiative tumor.