直肠癌术后复发再治疗的探讨

Treatment of postoperative local recurrence of rectal cancer.

目的 回顾性比较分析直肠癌术后局部复发不同治疗方法的疗效。方法 1990年 1月至 1997年 12月收治的直肠癌根治术后复发病人 15 4例 ,再次接受治疗 117例 ,其中Ⅰ组 (单纯手术 ) 4 4例 ,Ⅱ组 (手术切除加放疗 ) 2 8例 ,Ⅲ组 (单纯放疗 ) 4 5例。结果 Ⅰ、Ⅱ、Ⅲ及未治疗组中位存活期分别为 2 6 .8、2 1、14及 4个月。Ⅰ组1、3年生存率显著优于Ⅲ组 (P <0 .0 5 )。结论 提高直肠癌复发病人的疗效关键是密切随访 ,早期诊断 。

Objective\ To analyse retrospectively the therapeutic effects of various treatments for local recurrent rectal cancer after operation.Methods\ From 1990.1～1997.12,154 cases of local recurrent rectal cancer patients were studied,forty-four of them received operation (group Ⅰ),28 patients were treated by operation combined with radiotherapy (group Ⅱ) and 45 patients underwent radiotherapy only(group Ⅲ).The other 37 patients were untreated.Results\ The median survival time of group Ⅰ?Ⅱ?Ⅲ and unterated cases was 26 8?21?14 and 4 months respectively.The survival rates of group Ⅰ was better than group Ⅲ obviously(P<0 05).Conclusion\ Improvement can be expected from earlier diagnosis and synthetic therapy may result in good palliation and better effects.