高原适应初期对人体部分代谢的影响

CHANGES OF HUMAN ENERGY METABLISM IN EARLY EXPOSED TO HIGH ALTITUDE

目的 : 观察急进高原环境初期 ,缺氧等因素对人体能量代谢的影响 ;方法 :选择 75名青年急进高原 3 6小时及适应 60天后 ,分别采集血液标本测定血中乳酸 (LD)、乳酸脱氢酶 (LDH)、琥珀酸脱氢酶 (SDH)、黄嘌呤氧化酶 (XOD)、钠钾 -ATP酶 (Na+K+-ATP) ;结果 :进入高原 60天后比刚进入时血液中LD和LDH升高明显 (P <0 .0 1 ) ,SDH、XOD、Na+K+-ATP酶的活性比刚进入时均有明显下降 (P <0 .0 1 ) ;结论 :进入高原后 ,人体在适应高原缺氧环境过程中 ,机体的能量代谢方式发生一定的变化 ,向无氧酵解方式转移 ,造成有氧氧化减弱、部分酶活性下降 。

To study the effects of early exposed to high altitude on human energy metabolism.Method:75 youths, who exposeds to high altitude for 36 hrs and 60 days, were included in this study. The level of blood LD, LDH, SDH, XOD and Na +K +-ATP were examined at both stage. Results:The level of LD and LDH increased significantly (P<0.01) and the level of others were obviously decreased (P<0.01) after 60 days exposed than that after 36 hrs.Conclusion:The anaerobic metabolism is increased when the people expose to high altitude. The energy metabolism has some changes to adapt the mountain environment.