克百威 甲基对硫磷对湘云鲫脑AchE活性的影响

Effects of Carbofuran and Methyl-Parathion on AchE Activity in Brain of Xingyunji-Fish

采用体内染毒的方法,研究了克百威、甲基对硫磷及两者混合物对湘云鲫脑乙酰胆碱酯酶(AchE)活性的影响,对其作用机制和以AchE活性作为生物学标记物来监测环境中农药的可行性进行了初步的探讨。结果表明,克百威和甲基对硫磷之间产生协同作用,而且这种作用随时间的延长表现得更加显著,AchE活性可以作为生物学标记物。

This paper reports the effects of carbofuran and methylparathion onAchE Activity in Brain of Xingyunji-Fish. It also investigates their mechanisms and the possibility of AchE as a biomarker to monitor pesticide residues in environment. The results showed that interaction between the two pesticides exhibited to be synergistic, and became stronger with time, suggesting that the activity of AchE may be used as a biomarker.