保存真皮下血管网皮肤移植中血管重建的实验研究

TRANSPLANTATION OF SKIN WITH INTACT SUBDERMAL VASCULAR PLEXUS

本文采用家兔进行实验,在家兔动脉内灌注墨汁,观察保存真皮下血管网皮肤移植后不同时期墨汁在血管内的充盈状态,血运重建的过程。结果表明:(1)保留真皮下血管网皮肤移植后第2天血运开始建立;第3天血运增加;第7天血运基本完善。(2)保存真皮下血管网的游离皮肤移植后的血管重建过程,基本上通过移植片的真皮下血管网在切口周缘和基底部与受皮区的血管吻合。吻合处的血管为迂曲、扩张的薄壁血管。通过它们先与真皮内原有血管交通,并逐步在皮片内新生血管,建立起完整的血液循环。(3)皮片与受区随着吻合部位的不同,术后2天开始建立吻合,7天吻合最多,术后2周血管构筑基本完善。

Transplantation of skin with intact subdermal vascular plexus is a new type of skin graft. The transplanted tissues include all layers of the skin with its immediate vascular plexus. The anastomoses between the vessels of the graft and recipient site were studied in 6 rabbits. The animals were killed at at various intervals. And the vessels were perfused with Chinese ink mixed with 4% gelatin. After the perfusions, celloidin section for microscopic examination were made. The chief results were as follows: The subdermal vascular plexus survives easily when taken with its overlying skin. The reestablishment depends upon the anastomosis of the vessels on the edges and base of the graft with those of recipient site. This begins on the second post-operative day, is nearrly completed in 1 week and perfected by two weeks. The reestablishment of the circulation of the graft was discussed.