摘要
过氧化物酶尤其是从Caldariomycesfumago中得到的氯过氧化物酶 (CPO)能催化多种底物的氧化和环氧化反应 ,表现出良好的立体选择性 ,近年在此领域内的应用有若干重要的进展 .由于CPO与细胞色素P4 5 0单加氧酶的相似性 ,它们的反应机理与活性部位的研究也十分引人瞩目 .
Peroxidases, especially chloroperoxidase (CPO) from Caldariomyces fumago were applied to oxygenation and epoxidation of various substrates with high stereoselectivities. Some important results are documented in recent years. The exploration and comparison of mechanism and active site(s) of CPO and cytochrome P450 mono-oxygenase were also of great interest, due to their structural relevance.
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2002年第10期710-717,共8页
Chinese Journal of Organic Chemistry
