手征性二茂铁膦在催化不对称合成中的应用

Application of chiral ferrocenylphosphines In catalytic asymmetric synthesis

对手征性二茂铁膦的合成及其过渡金属配合物在催化不对称合成中的应用作了概述。讨论了手征性二茂铁烷基胺的不对称锂化反应机理,手征性二茂铁膦的镍、钯配合物催化不对称格氏偶合反应,钯、铂、铑配合物催化不对称硅氢化反应,铑配合物催化不对称氢化反应,钴配合物催化不对称氢迁移反应,钯配合物催化不对称环化反应,等等。

In this review,syntheses of chiral fer-rocenylphosphines and applications of theirtransition metal complexes are sammarized.Among the applications discussed are cataly-tic asymmetric Grignard cross-coupling byNi and Pd complexes,catalytie asymmetrichydrosilylation by Pd,Pt and Rh oomplexes,catalytic asymmetric hydrogenation by Rhcomplexes,and so on.