1[1]Diwan AD,Parvataneni HK,Khan SN,et al.Current concepts in intervertebral disc restoration.Orthop Clin N A 2000;31(3):453
2[2]Thompson JP,Oegema TR Jr,Bradford DS. Stimutation of mature canine intervertebral disc by gerowth factors.Spine 1991;16:253
3[3]Masuda K,Takegami K,Takegami K,et al.Recombiant osteogenic protein -1 upregulates extracellular matrix metabolism by rabbit anulus fibrosus and nucleus pulposus cells.Trans Orthop Res Soc 1999;24:1019
4[4]Nishida K,Kang JD,JK,et al.Adenovirus-mediated gene transfer to nucleus pulposus cells:Implications for the treatment of intertebral disc degeneration Spine 1998;23(22):2437
5[5]Nishida K,Kang JD,Gilbertson LG,et al.Modulation of the biologic activity of the rabbit intervertebral disc by gene therapy:An in vivo study of adenovirus-mediated transfer of the human transforming growth factors β1 encoding gene.Spine 1999;24:2419
6[6]Moon SH,Gilbertson LG,Nishida K,et al.Human intervertebral disc cells are genetically modifeable by adenovirus-mediated gene transfer:Implications for the clinical management of intervertebral disc disorders.Spine 2000;25(20):2573
7[7]Wehling P,Schulitz KP,Robbins PD,et al,Transfer of enes to chondrocytic cells of the iumbar spine:proposal for a treatment strategy of spinal disorder by local gene therapy.Spine 1997;10:1092
9[9]Yamagishi M,Nemoto H,Kikuchi T,et al. Ruptured human disc tissues produce matrix metalloproteinase-3 and interleukin-1.Trans Orthop Res Soc 1992;16:438
10[10]Takahashi H,Suguro T,Okazima Y,et al.Inflammotory cytokines in the herniated disc of the lumbar spine.Spine 1996;21:218
